De Angelis or de Angelis is a surname of Italian origin. The name refers to:
- Alberto de Angelis (fl. early 20th c.), Italian writer and biographer
- Alex de Angelis (b. 1984), Sammarinese Grand Prix motorcycle road racer
- April De Angelis (contemporary), British dramatist and playwright
- Catherine D. DeAngelis, MD, editor of the Journal of the American Medical Association
- Elio de Angelis (1958–1986), Italian Formula One race car driver
- Enrico De Angelis (fl. mid-20th c.), Italian singer
- Filippo de Angelis (1792–1877), Italian Roman Catholic cardinal
- Francesco De Angelis (musician) (b. 1971), Italian classical violinist
- Francesco de Angelis (b. 1960), Italian world championship sailboat racer
- Frankie DeAngelis (born 1986), Canadian professional ice hockey defenceman
- Guido & Maurizio De Angelis (contemporary), Italian composers and singers
- Jerome de Angelis (1567–1623), Italian Jesuit missionary to Japan; executed by fire
- Maximilian de Angelis (1889–1974), German general officer during WWII; POW 1945–55
- Milo de Angelis (b. 1951), Italian poet
- Nazzareno De Angelis (1881–1962), Italian operatic bass singer
- Richard De Angelis (1932 – 2005), American actor and comedian
- Roberto De Angelis (b. 1959), Italian comic book artist
- Rosemary De Angelis (b. 1933), American stage, film, and television actress
- Sandro DeAngelis (born 1981), Canadian gridiron football placekicker
- Tino De Angelis (b. 1915), American confidence man and commodities trader
- William De Angelis II (b. 1953), Professional Engineer
- Wilma De Angelis (b. 1931), Italian popular singer
| This page or section lists people with the surname De Angelis. If an internal link intending to refer to a specific person led you to this page, you may wish to change that link by adding the person's given name(s) to the link. |