Acting Career
Arquette has appeared in a number of movies including 1992's Buffy the Vampire Slayer (as Benny) and 1994's Airheads (as Carter). He also did guest spots on television shows like Blossom (1992), Beverly Hills, 90210 (1992), Friends (1996). Arquette also worked along side Drew Barrymore in the movie Never Been Kissed (1999) as her younger brother.
Arquette arguably achieved his biggest success in the horror/slasher film franchise Scream as Dewey Riley. It was during the filming of the first film in 1996 that he first met his future-wife: Courteney Cox. The couple married in 1999 (as their characters later did). Together, they appeared in a 2003 advertisement for Coke. The same year they formed production company Coquette (both a portmanteau of their last names and a word meaning a flirty woman) and have produced a number of films and television series, including Daisy Does America, Dirt, and Cougar Town, the latter two starring Courteney Cox-Arquette. Arquette has guest starred alongside Cox on the popular sitcom Friends in 1996 as well as Cougar Town on the third season's final episode in 2012.
Arquette appeared in the Sega video game ESPN NFL 2K5, voicing himself as a "celebrity adversary" and manager of his own team, the Los Angeles Locos, as well as appearing as an unlockable character in Season Mode. He also appeared in the 2001 EA video game SSX Tricky, as the voice of lead character Eddie.
Arquette starred alongside Jonathan Silverman and Kelly Hu in the 2007 ABC comedy series In Case of Emergency, which was canceled after one season after only airing 12 of its 13 episodes. Since then, he has appeared in the 2008 film Hamlet 2, as Gary, and reprised his role as Dewey Riley in Scream 4, again acting alongside his wife Courteney. He recently appeared alongside his sister in the TV show Medium on the January 7, 2011, episode.
He appeared in Rascal Flatts' music video for their song "Why Wait" in 2010.
Arquette, a well-known horror fan, made his directorial debut with 2007's The Tripper, and has recently signed on to direct Glutton, a '3D psychological thriller'. Glutton is scheduled to begin filming in July 2011 in Canada.
Arquette appeared on the 13th season of Dancing With The Stars, partnered with Kym Johnson. He was eliminated November 1, 2011.
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