People
Notable residents of County Tyrone have included:
- Hugh O'Neill, Earl of Tyrone (Aodh Mór Ó Néill), c.1550–1616, Irish leader during the Nine Years' War
- Philomena Begley, Irish country music singer
- Tom Clarke, a leader of the 1916 Easter Rising
- John Dunlap (1747–1812), publisher of the first American daily newspaper the Pennsylvania Packet in 1784, also the printer of the American Declaration of Independence.
- Janet Devlin, soul and pop artist and contestant on the Xfactor
- John Hughes, (1797–1864), born in Annaloghan, first Archbishop of Roman Catholic diocese of New York.
- Mary Mallon (1869–1938), more commonly known as Typhoid Mary
- Peter Canavan, former All Ireland winning Tyrone captain and second top scorer in Senior Ulster Championship football.
- Professor P G (Gerry) McKenna MRIA, biomedical scientist and former Vice Chancellor, University of Ulster
- Darren Clarke, professional golfer.
- Paul Brady, musician.
- Brian Dooher, former captain of the Tyrone senior football team.
- Hugo Duncan, singer and broadcaster on BBC Radio.
- Dennis Taylor, former World Snooker Champion.
- Aaron Hughes, current captain of the Northern Ireland football team and also plays for Fulham.
- Benedict Kiely (1919–2007), writer and broadcaster
- Thomas Mellon, founder of Mellon Bank, now Bank of New York Mellon
- Flann O'Brien, 1911–1966, writer
- Victor Sloan MBE, Visual Artist
- William Burke, 1792–1829, grave robber and murderer
- William Carleton, 1794–1869, writer
- Brian Friel, dramatist and theatre director
- Chloe Coyle, The All Ireland Talent Show (series 2)
- Ivan Sproule, football player for Bristol City F.C.
- Ryan Kelly, musician and member of Celtic Thunder
- James E. Boyd, seventh Governor of the state of Nebraska
- W. F. Marshall (1888 - 1954), the 'The Bard of Tyrone', Presbyterian minister, author and poet, creator of one of Northern Ireland's most popular dialect poems 'Me an' Me Da', and many others in similar vein, lecturer at Magee College Derry and leading authority on Mid Ulster English.
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“Those words freedom and opportunity do not mean a license to climb upwards by pushing other people down. Any paternalistic system that tries to provide for security for everyone from above only calls for an impossible task and a regimentation utterly uncongenial to the spirit of our people.”
—Franklin D. Roosevelt (1882–1945)