Uses in Chemical Synthesis
The uses for copper(II) acetate are more plentiful as a catalyst or oxidizing agent in organic syntheses. For example, Cu2(OAc)4 is used to couple two terminal alkynes to make a 1,3-diyne:
- Cu2(OAc)4 + 2 RC≡CH → 2 CuOAc + RC≡C-C≡CR + 2 HOAc
The reaction proceeds via the intermediacy of copper(I) acetylides, which are then oxidized by the copper(II) acetate, releasing the acetylide radical. A related reaction involving copper acetylides is the synthesis of ynamines, terminal alkynes with amine groups using Cu2(OAc)4.
Read more about this topic: Copper(II) Acetate
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