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- Daequan Cook (born April 28, 1987 in Dayton, Ohio) is an American basketball player and currently a shooting guard for the NBA's Oklahoma City Thunder.
- Dane Cook (born 1972), American comedian
- David Cook (disambiguation) several people
- Dennis Cook (born 1962) is an American former professional baseball pitcher.
- Dick Cook, Chairman of Disney Studios
- Doc Cook (Charles L. Cooke, 1891-1958), jazz bandleader
- Don Cook (born May 25, 1949 in San Antonio, Texas) is an American record producer and songwriter whose work is mainly in the field of country music.
- Don Cook (organist), organ area coordinator and the university carillonneur at Brigham Young University (BYU).
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