Presentation
The classic triad for congenital rubella syndrome is:
- Sensorineural deafness (58% of patients)
- Eye abnormalities—especially retinopathy, cataract and microphthalmia (43% of patients)
- Congenital heart disease—especially patent ductus arteriosus (50% of patients)
Other manifestations of CRS may include:
- Spleen, liver or bone marrow problems (some of which may disappear shortly after birth)
- Mental retardation
- Small head size (microcephaly)
- Eye defects
- Low birth weight
- Thrombocytopenic purpura (presents as a characteristic blueberry muffin rash)
- Hepatomegaly
- Micrognathia
Children who have been exposed to rubella in the womb should also be watched closely as they age for any indication of the following:
- Developmental delay
- Autism spectrum disorders
- Schizophrenia
- Growth retardation
- Learning disabilities
- Diabetes
- Glaucoma
Read more about this topic: Congenital Rubella Syndrome
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