Discovery of Coiled Coils
The possibility of coiled coils for α-keratin was proposed by Francis Crick in 1952 as well as mathematical methods for determining their structure. Remarkably, this was soon after the structure of the alpha helix was suggested in 1951 by Linus Pauling and coworkers.
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Famous quotes containing the words discovery of, discovery, coiled and/or coils:
“Your discovery of the contradiction caused me the greatest surprise and, I would almost say, consternation, since it has shaken the basis on which I intended to build my arithmetic.... It is all the more serious since, with the loss of my rule V, not only the foundations of my arithmetic, but also the sole possible foundations of arithmetic seem to vanish.”
—Gottlob Frege (1848–1925)
“Next to the striking of fire and the discovery of the wheel, the greatest triumph of what we call civilization was the domestication of the human male.”
—Max Lerner (b. 1902)
“Now remember courage, go to the door,
Open it and see whether coiled on the bed
Or cringing by the wall, a savage beast
Maybe with golden hair, with deep eyes
Like a bearded spider on a sunlit floor
Will snarl—and man can never be alone.”
—Allen Tate (1899–1979)
“Squalor spreads its hideous length
through the carts and the asses’ feet,
squalor coils and reopens
and creeps under barrow
and heap of refuse....”
—Hilda Doolittle (1886–1961)