Coiled Coil - Discovery of Coiled Coils

Discovery of Coiled Coils

The possibility of coiled coils for α-keratin was proposed by Francis Crick in 1952 as well as mathematical methods for determining their structure. Remarkably, this was soon after the structure of the alpha helix was suggested in 1951 by Linus Pauling and coworkers.

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Famous quotes containing the words discovery of, discovery, coiled and/or coils:

    He is not a true man of science who does not bring some sympathy to his studies, and expect to learn something by behavior as well as by application. It is childish to rest in the discovery of mere coincidences, or of partial and extraneous laws. The study of geometry is a petty and idle exercise of the mind, if it is applied to no larger system than the starry one.
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    We are all humiliated by the sudden discovery of a fact which has existed very comfortably and perhaps been staring at us in private while we have been making up our world entirely without it.
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    Now remember courage, go to the door,
    Open it and see whether coiled on the bed
    Or cringing by the wall, a savage beast
    Maybe with golden hair, with deep eyes
    Like a bearded spider on a sunlit floor
    Will snarl—and man can never be alone.
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    Squalor spreads its hideous length
    through the carts and the asses’ feet,
    squalor coils and reopens
    and creeps under barrow
    and heap of refuse....
    Hilda Doolittle (1886–1961)