Coiled Coil - Discovery of Coiled Coils

Discovery of Coiled Coils

The possibility of coiled coils for α-keratin was proposed by Francis Crick in 1952 as well as mathematical methods for determining their structure. Remarkably, this was soon after the structure of the alpha helix was suggested in 1951 by Linus Pauling and coworkers.

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Famous quotes containing the words discovery of, discovery, coiled and/or coils:

    However backwards the world has been in former ages in the discovery of such points as GOD never meant us to know,—we have been more successful in our own days:Mthousands can trace out now the impressions of this divine intercourse in themselves, from the first moment they received it, and with such distinct intelligence of its progress and workings, as to require no evidence of its truth.
    Laurence Sterne (1713–1768)

    Your discovery of the contradiction caused me the greatest surprise and, I would almost say, consternation, since it has shaken the basis on which I intended to build my arithmetic.... It is all the more serious since, with the loss of my rule V, not only the foundations of my arithmetic, but also the sole possible foundations of arithmetic seem to vanish.
    Gottlob Frege (1848–1925)

    Now remember courage, go to the door,
    Open it and see whether coiled on the bed
    Or cringing by the wall, a savage beast
    Maybe with golden hair, with deep eyes
    Like a bearded spider on a sunlit floor
    Will snarl—and man can never be alone.
    Allen Tate (1899–1979)

    Squalor spreads its hideous length
    through the carts and the asses’ feet,
    squalor coils and reopens
    and creeps under barrow
    and heap of refuse....
    Hilda Doolittle (1886–1961)