Discovery of Coiled Coils
The possibility of coiled coils for α-keratin was proposed by Francis Crick in 1952 as well as mathematical methods for determining their structure. Remarkably, this was soon after the structure of the alpha helix was suggested in 1951 by Linus Pauling and coworkers.
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Famous quotes containing the words discovery of, discovery, coiled and/or coils:
“That the discovery of this great truth, which lies so near and obvious to the mind, should be attained to by the reason of so very few, is a sad instance of the stupidity and inattention of men, who, though they are surrounded with such clear manifestations of the Deity, are yet so little affected by them, that they seem as it were blinded with excess of light.”
—George Berkeley (1685–1753)
“Next to the striking of fire and the discovery of the wheel, the greatest triumph of what we call civilization was the domestication of the human male.”
—Max Lerner (b. 1902)
“Now remember courage, go to the door,
Open it and see whether coiled on the bed
Or cringing by the wall, a savage beast
Maybe with golden hair, with deep eyes
Like a bearded spider on a sunlit floor
Will snarl—and man can never be alone.”
—Allen Tate (1899–1979)
“Squalor spreads its hideous length
through the carts and the asses’ feet,
squalor coils and reopens
and creeps under barrow
and heap of refuse....”
—Hilda Doolittle (1886–1961)