Central Pontine Myelinolysis - Causes

Causes

The most common cause is the too rapid correction of low blood sodium levels (hyponatremia).

It has also been known to occur in patients suffering withdrawal symptoms of chronic alcoholism. In these instances, occurrence may be entirely unrelated to hyponatremia or rapid correction of hyponatremia.

It has been observed following hematopoietic stem cell transplantation.

CPM may also occur in patients affected by

• severe liver disease
• liver transplant
• alcoholism
• severe burns
• malnutrition
• anorexia
• severe electrolyte disorders
• AIDS
• hyperemesis gravidarum.