The second, more commonly known as Salisbury House, was built on the waterfront opposite the existing house, by Burghley's younger son Robert Cecil, created Earl of Salisbury, around the turn of the 17th century. It was divided by his heir the second Earl into two parts, of which the lesser was demolished in 1678 to make room for a new residential street, Salisbury Street. The central part of the building was converted to shops and officially renamed the Middle Exchange, though colloquially the building was of ill repute, being known as the "Whores' Nest"; this part of the building was finally demolished around 1695, along with the remainder of the house, to make room for a new road named Cecil Street. The site was subsequently used for the Hotel Cecil, named after this house, and is currently occupied by Shell Mex House.
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