A binding domain is a protein domain which binds to a specific atom or molecule, such as calcium or DNA. Upon binding, proteins may undergo a conformational change. Binding domains are essential for the function of many proteins.
Examples of binding domains include Zinc finger, which binds to DNA, and EF hand, which binds to calcium.
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Famous quotes containing the words binding and/or domain:
“What is lawful is not binding only on some and not binding on others. Lawfulness extends everywhere, through the wide-ruling air and the boundless light of the sky.”
—Empedocles 484424 B.C., Greek philosopher. The Presocratics, p. 142, ed. Philip Wheelwright, The Bobbs-Merrill Co., Inc. (1960)
“Without metaphor the handling of general concepts such as culture and civilization becomes impossible, and that of disease and disorder is the obvious one for the case in point. Is not crisis itself a concept we owe to Hippocrates? In the social and cultural domain no metaphor is more apt than the pathological one.”
—Johan Huizinga (18721945)