Incidence/prevalence
Bicuspid aortic valves are the most common cardiac valvular anomaly, occurring in 1- 2% of the general population. It is twice as common in males as in females.
Bicuspid aortic valve is an inheritable condition, with a demonstrated association with Notch 1. Both familial clustering and isolated valve defects have been documented. The incidence of bicuspid aortic valve can be as high as 10% in families affected with the valve problem. Recent studies suggest that BAV is an autosomal dominant condition with incomplete penetrance. Other congenital heart defects are associated with bicuspid aortic valve at various frequencies, including coarctation of the aorta.
Read more about this topic: Bicuspid Aortic Valve
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