Diseases
Some diseases result from a poorly functioning basement membrane. The cause can be genetic defects, injuries by the body's own immune system, or other mechanisms.
Genetic defects in the collagen fibers of the basement membrane cause Alport syndrome.
Non-collagenous domain basement membrane collagen type IV is autoantigen (target antigen) of autoantibodies in the autoimmune disease Goodpasture's syndrome.
A group of diseases stemming from improper function of basement membrane zone are united under the name epidermolysis bullosa.
Read more about this topic: Basement Membrane
Famous quotes containing the word diseases:
“A fiction about soft or easy deaths ... is part of the mythology of most diseases that are not considered shameful or demeaning.”
—Susan Sontag (b. 1933)
“But what is quackery? It is commonly an attempt to cure the diseases of a man by addressing his body alone. There is need of a physician who shall minister to both soul and body at once, that is, to man. Now he falls between two stools.”
—Henry David Thoreau (1817–1862)
“Arrogance, pedantry, and dogmatism ... the occupational diseases of those who spend their lives directing the intellects of the young.”
—Henry S. Canby (1878–1961)