An aromatic amine is an amine with an aromatic substituent - that is -NH2, -NH- or nitrogen group(s) attached to an aromatic hydrocarbon, whose structure usually contains one or more benzene rings. Aniline is the simplest example.
Aromatic amines, when protonated, usually have lower pKa's (are more acidic) than their non-aromatic analogs. This is due to the delocalization of the lone pair of electrons from the nitrogen into the ring.
Representative anilines | |||||
Aromatic amine | CAS number | Properties | Uses | ||
Aniline | 62-53-3 | ||||
o-Toluidine | 95-53-4 | ||||
2,4,6-Trimethylaniline | 88-05-1 | ||||
Anisidine | 90-04-0 | ||||
3-Trifluoromethylaniline | 98-16-8 | Intermediate for herbicides, metabolite | |||
N-Methylaniline | 100-61-8 |
The general population is exposed to aromatic amines through the diet (e.g. pesticides), pharmaceuticals (e.g. prilocain), hair dyes, smoking, diesel engine exhaust as well as through occupational exposure at the workplace (e.g. rubber, textiles, dye industries).
Read more about Aromatic Amine: Aromatic Amines in Textiles
Famous quotes containing the word aromatic:
“Die of a rose in aromatic pain?”
—Alexander Pope (16881744)