Annia Cornificia Faustina (122/123-between 152-158) was the youngest child and only daughter to Praetor Marcus Annius Verus and Domitia Lucilla. The parents of Cornificia came from wealthy senatorial families who were of consular rank. She was born and raised in Rome. The brother of Cornificia was the future Roman Emperor Marcus Aurelius.
In 124, the father of Cornificia had died. She and her brother were raised by their mother and their paternal grandfather the Roman Senator Marcus Annius Verus. Her paternal grandfather had died in 138. Relations between her and her brother appeared to be good. Before Cornificia had married, she had settled her paternal inheritance with her brother.
Cornificia married the Roman Senator Gaius Ummidius Quadratus Annianus Verus, who served as a suffect consul in 146. Annianus Verus had descended from one of the leading aristocratic and political influential families in Rome. He was a direct descendant of the late suffect consul Gaius Ummidius Durmius Quadratus.
Cornificia bore Annianus Verus two children who were:
- Marcus Ummidius Quadratus Annianus
- Ummidia Cornificia Faustina