Albrecht Kossel - Early Research and Collaboration

Early Research and Collaboration

After completing his university studies, Kossel returned to the University of Strasbourg as research assistant to Felix Hoppe-Seyler. At the time, Hoppe-Seyler was intensely interested in research concerning an acidic substance that had first been chemically isolated from pus cells by one of his former students, Friedrich Miescher, in 1869. Unlike protein, the substance contained considerable amounts of phosphorus, but with its high acidity, it was unlike any cellular substance that had to then been observed.

Kossel showed that the substance, called "nuclein", consisted of a protein component and a non-protein component. Kossel further isolated and described the non-protein component. This substance has become known as nucleic acid, which contains the genetic information found in all living cells.

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