Work
As late as the 1840s, and despite Friedrich Wöhler's synthesis of urea in 1828, some chemists still believed in the doctrine of vitalism, according to which a special life-force was necessary to create organic compounds. Kolbe developed the idea that organic compounds could be derived from inorganic ones, directly or indirectly, by substitution processes. He validated his theory by converting carbon disulfide, in several steps, to acetic acid (1843–45). Introducing a modified idea of structural radicals, he contributed to the establishment of structural theory. One of the more dramatic successes of his theory was his prediction of the existence of secondary and tertiary alcohols, a conjecture that was soon confirmed by the synthesis of these substances.
He worked on the electrolysis of the salts of fatty and other acids (Kolbe electrolysis) and prepared salicylic acid, a building block of aspirin in a process called Kolbe synthesis or Kolbe-Schmitt reaction. A certain method for the synthesis of nitriles is called the Kolbe nitrile synthesis.
Hermann Kolbe was the first person to use the word synthesis in the present day meaning.
With Edward Frankland he found that nitriles can be hydrolyzed to the corresponding acids.
Read more about this topic: Adolph Wilhelm Hermann Kolbe
Famous quotes containing the word work:
“We have not the motive to prepare ourselves for a “life-work” of teaching, of social work—we know that we would lay it down with hallelujah in the height of our success, to make a home for the right man. And all the time in the background of our consciousness rings the warning that perhaps the right man will never come. A great love is given to very few. Perhaps this make-shift time filler of a job is our life work after all.”
—Ruth Benedict (1887–1948)
“If therefore my work is negative, irreligious, atheistic, let it be remembered that atheism—at least in the sense of this work—is the secret of religion itself; that religion itself, not indeed on the surface, but fundamentally, not in intention or according to its own supposition, but in its heart, in its essence, believes in nothing else than the truth and divinity of human nature.”
—Ludwig Feuerbach (1804–1872)
“When I consider thy heavens, the work of thy fingers, the moon and the stars, which thou hast ordained;
What is man, that thou art mindful of him?”
—Bible: Hebrew Psalm VIII (l. VIII, 3–4)