Interesting Examples
Accessing an individual byte frequently requires reading or writing the full bus width (a word) at once. In these instances the least significant bits of the address bus may not even be implemented - it is instead the responsibility of the controlling device to isolate the individual byte required from the complete word transmitted. This is the case, for instance, with the VESA Local Bus which lacks the two least significant bits, limiting this bus to aligned 32-bit transfers.
Historically, there were also some examples of computers which were only able to address words.
Read more about this topic: Address Bus
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