Adaptive Optics - in Retinal Imaging

In Retinal Imaging

Ocular aberrations are distortions in the wavefront passing through the pupil of the eye. These aberrations diminish the quality of the image formed on the retina, sometimes necessitating the wearing of spectacles or contact lenses. In the case of retinal imaging, light passing out of the eye carries similar wavefront distortions, leading to an inability to resolve the microscopic structure (cells and capillaries) of the retina. Spectacles and contact lenses correct "low-order aberrations", such as defocus and astigmatism, which tend to be stable in humans for long periods of time (months or years). While correction of these is sufficient for normal visual functioning, it is generally insufficient to achieve microscopic resolution. Additionally, "high-order aberrations", such as coma, spherical aberration, and trefoil, must also be corrected in order to achieve microscopic resolution. High-order aberrations, unlike low-order, are not stable over time, and may change with frequencies between 10 Hz and 100 Hz. The correction of these aberrations requires continuous, high-frequency measurement and compensation.