Acetylcholine Receptor - Receptor Types

Receptor Types

Molecular biology has shown that the nicotinic and muscarinic receptors belong to distinct protein superfamilies.

ACh and its receptors
Drug Nm Nn M1 M2 M3
ACh, Charbacol, AChEi (Psysostigmine, Galantamine, Neostigmine, Pyridostigmine) + + + + +
Nicotine, Varenicline + +
Succinylcholine +/-
Atracurium, Vecuronium, Tubocurarine, Pancuronium -
Epibatidine, DMPP +
Trimethaphan, Mecamylamine, Bupropion, Dextromethophan, Hexamethonium -
Muscarine, Methacholine, Oxotremorine, Bethanechol, Pilocarpine + + +
Atropine, Tolterodine, Oxybutynin - - -
Vedaclidine, Talsaclidine, Xanomeline, Ipatropium +
Pirenzepine, Telenzepine -
Methoctramin -
Darifenacin, 4-DAMP, Darifenacin, Solifenacin -

Read more about this topic:  Acetylcholine Receptor

Famous quotes containing the words receptor and/or types:

    “The disinterest [of my two great-aunts] in anything that had to do with high society was such that their sense of hearing ... put to rest its receptor organs and allowed them to suffer the true beginnings of atrophy.”
    —Marcel Proust (1871–1922)

    “If there is nothing new on the earth, still the traveler always has a resource in the skies. They are constantly turning a new page to view. The wind sets the types on this blue ground, and the inquiring may always read a new truth there.”
    —Henry David Thoreau (1817–1862)