Receptor Types
Molecular biology has shown that the nicotinic and muscarinic receptors belong to distinct protein superfamilies.
| Drug | Nm | Nn | M1 | M2 | M3 |
|---|---|---|---|---|---|
| ACh, Charbacol, AChEi (Psysostigmine, Galantamine, Neostigmine, Pyridostigmine) | + | + | + | + | + |
| Nicotine, Varenicline | + | + | |||
| Succinylcholine | +/- | ||||
| Atracurium, Vecuronium, Tubocurarine, Pancuronium | - | ||||
| Epibatidine, DMPP | + | ||||
| Trimethaphan, Mecamylamine, Bupropion, Dextromethophan, Hexamethonium | - | ||||
| Muscarine, Methacholine, Oxotremorine, Bethanechol, Pilocarpine | + | + | + | ||
| Atropine, Tolterodine, Oxybutynin | - | - | - | ||
| Vedaclidine, Talsaclidine, Xanomeline, Ipatropium | + | ||||
| Pirenzepine, Telenzepine | - | ||||
| Methoctramin | - | ||||
| Darifenacin, 4-DAMP, Darifenacin, Solifenacin | - |
Read more about this topic: Acetylcholine Receptor
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