An ACE inhibitor (or angiotensin-converting-enzyme inhibitor) is a medication pharmaceutical drug used primarily for the treatment of high blood pressure (hypertension) and weak heart muscle. (congestive heart failure).
This group of drugs causes dilation of blood vessels which results in lower blood pressure. In treating heart disease ACE inhitors are usually used with other medications. A typical treatment plan will often include an ACE inhibitor, beta blocker, a long acting nitrate and a calcium channel blocker in combinations that are adjusted to the individual patient's needs.
After a patient is started on an ACE inhibitor, an EKG (electrocardiogram) will be done to evaluate the effect the drug may have on the heart rhythm. Dosage may be changed after the patient's EKG is examined.
Originally synthesized from compounds found in pit viper venom, ACE inhibitors inhibit angiotensin-converting enzyme (a component of the blood pressure-regulating renin-angiotensin system), thereby decreasing the tension of blood vessels and blood volume, thus lowering blood pressure.
Frequently prescribed ACE inhibitors include perindopril, captopril, enalapril, lisinopril, and ramipril.
Read more about ACE Inhibitor: Medical Use, Mechanism of Action, Adverse Effects, Contraindications and Precautions, Comparative Information, Angiotensin II Receptor Antagonists, History
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