Significant Persons
- Aetius, last of the great Roman generals
- Alaric I, king of the Visigoths that sacked Rome
- Aspar, Eastern Roman general and politician
- Attila the Hun, king of the Huns
- Augustine of Hippo, bishop, theologian
- Bahram V, Sassanid Shah of Persia
- Bodhidharma, founder of Chan Buddhism
- Boniface, Roman comes in charge of the province of Africa
- John Chrysostom, Patriarch of Constantinople
- Clovis, first Frankish king to unite the Franks; first barbarian king to convert to Catholicism
- Cyril of Alexandria, Patriarch of Alexandria, theologian
- Dioscorus, patriarch of Alexandria
- Faxian, Chinese Buddhist monk
- Geiseric, Vandal king and founder of the Vandal kingdom in North Africa
- Gelasius, bishop of Rome
- Huiyuan, Chinese Buddhist
- Hypatia of Alexandria, woman philosopher
- Jerome, Christian hermit, priest, Latin translator of Bible and other theological works
- John Cassian, Christian monk and theologian
- Kumarajiva, (344-413), Kuchean Buddhist monk and Chinese translator
- Leo I, bishop of Rome, theologian
- Saint Mesrob, Armenian monk
- Nestorius, archbishop of Constantinople, father of Nestorian heresy
- Niall Noigiallach, founder of one of Ireland's greatest dynasties
- Patrick, (Patricius) Catholic bishop, missionary to Ireland
- Pelagius, Catholic priest father of Pelagianism
- Ricimer, Western Roman general, politician and ruler
- Riothamus, King of the Britons, a candidate for the legendary King Arthur
- Tyrannius Rufinus, priest of Aquileia, hermit, Latin translator
- Socrates Scholasticus, Byzantine Church historian
- Sozomen, Christian church historian
- Theoderic the Great, Ostrogothic king
- Yazdegerd I, Sassanid Shah of Persia
- Zu Chongzhi, Chinese astronomer and mathematician
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