In enzymology, a 5-guanidino-2-oxopentanoate decarboxylase (EC 4.1.1.75) is an enzyme that catalyzes the chemical reaction
- 5-guanidino-2-oxo-pentanoate 4-guanidinobutanal + CO2
Hence, this enzyme has one substrate, 5-guanidino-2-oxo-pentanoate, and two products, 4-guanidinobutanal and CO2.
This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 5-guanidino-2-oxo-pentanoate carboxy-lyase (4-guanidinobutanal-forming). Other names in common use include alpha-ketoarginine decarboxylase, and 2-oxo-5-guanidinopentanoate carboxy-lyase. It has 2 cofactors: thiamin diphosphate, and Divalent cation.