5-aminovalerate Transaminase

In enzymology, a 5-aminovalerate transaminase (EC 2.6.1.48) is an enzyme that catalyzes the chemical reaction

5-aminopentanoate + 2-oxoglutarate 5-oxopentanoate + L-glutamate

Thus, the two substrates of this enzyme are 5-aminopentanoate and 2-oxoglutarate, whereas its two products are 5-oxopentanoate and L-glutamate.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is 5-aminopentanoate:2-oxoglutarate aminotransferase. Other names in common use include 5-aminovalerate aminotransferase, delta-aminovalerate aminotransferase, and delta-aminovalerate transaminase. This enzyme participates in lysine degradation. It employs one cofactor, pyridoxal phosphate.