Production and Inhibition
The enzyme is produced in many tissues in both males and females especially in tissues of the reproductive tract, testis and ovary, namely the skin, seminal vesicles, prostate, epididymis and many organs.
Inhibition of 5α-reductase results in decreased conversion of T to DHT, increased levels of testosterone, and, perhaps, increased levels of estradiol. Gynecomastia, erectile dysfunction and depression, are only a few of the possible side-effects of 5α-reductase inhibition. Long term side effects, that continued even after discontinuation of the drug, are called "Post-Finasteride Syndrome".
Read more about this topic: 5-alpha Reductase
Famous quotes containing the words production and and/or production:
“Production and consumption are the nipples of modern society. Thus suckled, humanity grows in strength and beauty; rising standard of living, all modern conveniences, distractions of all kinds, culture for all, the comfort of your dreams.”
—Raoul Vaneigem (b. 1934)
“The problem of culture is seldom grasped correctly. The goal of a culture is not the greatest possible happiness of a people, nor is it the unhindered development of all their talents; instead, culture shows itself in the correct proportion of these developments. Its aim points beyond earthly happiness: the production of great works is the aim of culture.”
—Friedrich Nietzsche (1844–1900)