4-hydroxyphenylpyruvate Decarboxylase

In enzymology, a 4-hydroxyphenylpyruvate decarboxylase (EC 4.1.1.80) is an enzyme that catalyzes the chemical reaction

4-hydroxyphenylpyruvate 4-hydroxyphenylacetaldehyde + CO₂

Hence, this enzyme has one substrate, 4-hydroxyphenylpyruvate, and two products, 4-hydroxyphenylacetaldehyde and CO₂.

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 4-hydroxyphenylpyruvate carboxy-lyase (4-hydroxyphenylacetaldehyde-forming). This enzyme is also called 4-hydroxyphenylpyruvate carboxy-lyase.