4-hydroxynonenal

4-Hydroxynonenal

4-Hydroxynonenal, or 4-hydroxy-2-nonenal or 4-HNE or HNE, (C₉H₁₆O₂), is an α,β-unsaturated hydroxyalkenal which is produced by lipid peroxidation in cells. 4-HNE is the primary alpha,beta-unsaturated hydroxyalkenal formed in this process.