4-hydroxybenzoyl-Co A Thioesterase

4-hydroxybenzoyl-Co A Thioesterase

In enzymology, a 4-hydroxybenzoyl-CoA thioesterase (EC 3.1.2.23) is an enzyme that catalyzes the chemical reaction

4-hydroxybenzoyl-CoA + H₂O 4-hydroxybenzoate + CoA

Thus, the two substrates of this enzyme are 4-hydroxybenzoyl-CoA and H₂O, whereas its two products are 4-hydroxybenzoate and CoA.

This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name of this enzyme class is 4-hydroxybenzoyl-CoA hydrolase. This enzyme participates in 2,4-dichlorobenzoate degradation.