3-Quinuclidinyl Benzilate - History

History

One of the anticholinergic compounds, 3-quinuclidinyl benzilate, was assigned the NATO code BZ and was weaponized at the beginning of the 1960s for possible battlefield use. BZ was invented by Hoffman-LaRoche in 1951. The company was investigating anti-spasmodic agents, similar to tropine, for treating gastrointestinal issues when the chemical was discovered. In 1959 the United States Army began to show interest in using the chemical as a chemical warfare agent. The agent was originally designated TK but when it was standardized by the U.S. Army in 1961 it was designated BZ. The agent commonly became known as "Buzz" because of this abbreviation and the effects it had on the mental state of its casualties.

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