Chemistry
Preparation of 3-quinuclidone (c.f. quinuclidine) has been documented.
The last step of the procedure appears to be a Dieckmann cyclization (intramolecular Claisen condensation) followed by decarboxylation.
Additionally, benzilic acid is made in a few steps starting from benzaldehyde and cyanide catalyst.
3-Quinuclidone is a drug precursor for medicinal (neuroprotective) as well as military applications, c.f. PNU-282,987.
Read more about this topic: 3-Quinuclidinyl Benzilate
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