3-hydroxy-3-methylglutaryl-Co A Lyase

3-hydroxy-3-methylglutaryl-Co A Lyase

3-hydroxy-3-methylglutaryl-CoA lyase (or HMG-CoA lyase) plays an essential role in breaking down dietary proteins and fats for energy.

Specifically, the enzyme is required for ketogenesis in the liver, and is also responsible for processing the amino acid leucine.