Schedule
| Date | Time | Opponent# | Rank# | Site | TV | Result | Attendance | |
|---|---|---|---|---|---|---|---|---|
| September 4 | 8:00 PM | at #11 Miami | #10 | Miami Orange Bowl • Miami, FL (Rivalry) | ESPN | W 13–10 | 71,481 | |
| September 9 | 6:00 PM | Troy* | #9 | Doak Campbell Stadium • Tallahassee, FL | W 24–17 | 77,217 | ||
| September 16 | 7:45 PM | Clemson | #10 | Doak Campbell Stadium • Tallahassee, FL (Rivalry/Bowden Bowl) | ESPN | L 20–27 | 83,510 | |
| September 23 | 3:30 PM | Rice* | #17 | Doak Campbell Stadium • Tallahassee, FL | ESPNU | W 55–7 (vacated) | 78,154 | |
| October 5 | 7:30 PM | at NC State | #16 | Carter–Finley Stadium • Raleigh, NC | ESPN | L 20–24 | 57,437 | |
| October 14 | 1:00 PM | at Duke | Wallace Wade Stadium • Durham, NC | W 51–24 (vacated) | 17,525 | |||
| October 21 | 3:30 PM | #21 Boston College | Doak Campbell Stadium • Tallahassee, FL | ABC | L 19–24 | 83,043 | ||
| October 28 | 7:00 PM | at Maryland | Byrd Stadium • College Park, MD | ESPN2 | L 24–27 | 50,517 | ||
| November 4 | 12:00 PM | Virginia | Doak Campbell Stadium • Tallahassee, FL (Jefferson–Eppes Trophy) | Raycom/LFS | W 33–0 (vacated) | 82,804 | ||
| November 11 | 8:00 PM | #19 Wake Forest | Doak Campbell Stadium • Tallahassee, FL | ABC | L 30–0 | 77,785 | ||
| November 18 | 2:00 PM | Western Michigan* | Doak Campbell Stadium • Tallahassee, FL | W 28–20 (vacated) | 78,236 | |||
| November 25 | 12:00 PM | #4 Florida* | Doak Campbell Stadium • Tallahassee, FL (Battle for the Governor's Cup) | ABC | L 14–21 | 83,507 | ||
| December 27 | 8:00 PM | vs. UCLA* | AT&T Park • San Francisco, CA (Emerald Bowl) | ESPN | W 44–27 (vacated) | 40,331 | ||
Read more about this topic: 2006 Florida State Seminoles Football Team