Schedule
| Date | Time | Opponent# | Rank# | Site | TV | Result | Attendance | |
|---|---|---|---|---|---|---|---|---|
| September 2 | 3:30 p.m. | Florida Atlantic* | #18 | Memorial Stadium • Clemson, SC | ESPNU | W 54–6 | 78,693 | |
| September 9 | 3:30 p.m. | at Boston College | #18 | Alumni Stadium • Chestnut Hill, MA | ABC | L 34–33 2OT | 44,500 | |
| September 16 | 7:45 p.m. | at #10 Florida State | Doak Campbell Stadium • Tallahassee, FL (Clemson-Florida State Rivalry) | ESPN | W 27–20 | 83,510 | ||
| September 23 | 12:00 p.m. | North Carolina | #23 | Memorial Stadium • Clemson, SC | Raycom/LFS | W 52–7 | 81,886 | |
| September 30 | 7:00 p.m. | Louisiana Tech* | #19 | Memorial Stadium • Clemson, SC | ESPNU | W 51–0 | 81,564 | |
| October 7 | 12:00 p.m. | at Wake Forest | #15 | Groves Stadium • Winston-Salem, NC | ESPN | W 27–17 | 35,920 | |
| October 12 | 7:30 p.m. | vs. Temple* | #12 | Bank of America Stadium • Charlotte, NC | ESPNU | W 63–9 | 30,246 | |
| October 21 | 7:45 p.m. | #13 Georgia Tech | #12 | Memorial Stadium • Clemson, SC | ESPN | W 31–7 | 82,630 | |
| October 26 | 7:45 p.m. | at Virginia Tech | #11 | Lane Stadium • Blacksburg, VA | ESPN | L 24–7 | 66,233 | |
| November 4 | 12:00 p.m. | Maryland | #19 | Memorial Stadium • Clemson, SC | ESPN2 | L 13–12 | 80,556 | |
| November 11 | 12:00 p.m. | NC State | Memorial Stadium • Clemson, SC (Textile Bowl) | Raycom/LFS | W 20–14 | 81,785 | ||
| November 25 | 12:00 p.m. | South Carolina* | #24 | Memorial Stadium • Clemson, SC (Battle for the Palmetto State) | ESPN | L 31–28 | 83,428 | |
| December 29 | 1:00 p.m. | vs. Kentucky* | LP Field • Nashville, TN (Music City Bowl) | ESPN | L 28–20 | 68,024 | ||
Read more about this topic: 2006 Clemson Tigers Football Team