Other Significant Singles
See also: :Category:1980 singles
- "9:30 May 2" – The Minutemen
- "11 O'Clock Tick Tock" – U2
- "Aap Jaisa Koi" – Nazia Hassan
- "A Day Without Me" – U2
- "A Forest" – The Cure
- "Ace of Spades" – Motörhead
- "Against the Wind" – Bob Seger and the Silver Bullet Band
- "Ah! Leah!" – Donnie Iris
- "Alabama Getaway" – Grateful Dead
- "All I Do" – Stevie Wonder
- "All Night Long" – Joe Walsh
- "All Night Long" – Rainbow
- "All Out of Love" – Air Supply
- "All Over the World" – Electric Light Orchestra
- "All the Way From America" – Joan Armatrading
- "American Generation" – Ritchie Family
- "Amsterdam" -Maggie MacNeal
- "And the Beat Goes On" – The Whispers
- "And the Cradle Will Rock..." – Van Halen
- "Another Day" – U2
- "Another Nail in My Heart" – Squeeze
- "Antmusic" – Adam and the Ants
- "Any Way You Want It" – Journey
- "Army Dreamers" – Kate Bush
- "Atmosphere/She's Lost Control" – Joy Division
- "Atomic" – Blondie
- "Babe" – Styx
- "Babooshka" – Kate Bush
- "Babylon Sisters" – Steely Dan
- "Back in Black" – AC/DC
- "Back Together Again" – Roberta Flack and Donny Hathaway
- "Baggy Trousers" – Madness
- "Beautiful Boy (Darling Boy)" – John Lennon
- "Behind the Groove" – Teena Marie
- "Better Love Next Time" – Dr. Hook
- "Betty Lou's Gettin' Out Tonight" – Bob Seger and the Silver Bullet Band
- "The Biggest Part of Me" – Ambrosia
- "Biko" – Peter Gabriel
- "Blackman Redemption" – Bob Marley & the Wailers
- "The Boat Family" – The Roches
- "Born Under Punches (The Heat Goes On)" – Talking Heads
- "Boulevard" – Jackson Browne
- "Breakdown Dead Ahead" – Boz Scaggs
- "Breathing" – Kate Bush
- "Broken English" – Marianne Faithfull
- "Buffalo Soldier" – Bob Marley & The Wailers, recorded in 1980, but unreleased until 1983, after Bob Marley's death in 1981.
- "Butcher Baby/Tight Black Pants" – Plasmatics
- "By The Author of Psycho" – The Couch (proto-Drum and bass)
- "The Call Up" – The Clash
- "Can You Feel It" – The Jacksons
- "Can't Help Myself" – Flowers
- "Captain Kennedy" – Neil Young
- "Career Opportunities" – The Clash
- "Cars (song)" – Gary Numan
- "Carrie" – Cliff Richard
- "Celebration" – Kool & the Gang
- "Chant Down Babylon" – Bob Marley & The Wailers
- "Chemical Warfare" – Dead Kennedys
- "Chinatown" – Thin Lizzy
- "Cities" – Talking Heads
- "City Hobgoblins" – The Fall
- "Clampdown" – The Clash
- "Cleanup Time" – John Lennon
- "Clones (We're All)" – Alice Cooper
- "Clubland" – Elvis Costello and the Attractions
- "Columbus" – Burning Spear
- "Come Back" – The J. Geils Band
- "Come to Me" – France Joli
- "Comfortably Numb" – Pink Floyd (released in 1979)
- "Coming Up" – Paul McCartney
- "Cool Change" – Little River Band
- "Could I Have This Dance" – Anne Murray
- "Could You Be Loved" – Bob Marley & The Wailers
- "Coward of the County" – Kenny Rogers
- "Crazy Train" – Ozzy Osbourne's Blizzard of Oz
- "Christine" – Siouxsie and the Banshees
- "Crosseyed and Painless" – Talking Heads
- "Cruisin'" – Smokey Robinson
- "Cry Blood Africans" – Burning Spear
- "Cupid/I've Loved You for a Long Time" – The Spinners
- "Dance (Pt. 1)" – The Rolling Stones
- "Dance Stance" – Dexys Midnight Runners
- "Dancing with Myself" – Generation X
- "Decades" – Joy Division
- "December Will Be Magic Again" – Kate Bush
- "De Do Do Do, De Da Da Da" - The Police
- "Déjà Vu" – Dionne Warwick
- "Desire" – Andy Gibb
- "Disco Apocalypse" – Jackson Browne
- "Disco Circus" – Martin Circus
- "Do Nothing" – The Specials
- "Do You Dream In Colour?" – Bill Nelson
- "Do You Love What You Feel" – Rufus featuring Chaka Khan
- "Do You Remember Rock 'n' Roll Radio?" – Ramones
- "Dog Eat Dog" – Adam and the Ants
- "Don't Ask Me Why" – Billy Joel
- "Don't Bring Me Down" – Electric Light Orchestra
- "Don't Do Me Like That" – Tom Petty and the Heartbreakers
- "Don't Ease Me In" – Grateful Dead
- "Don't Fall in Love with a Dreamer" – Kenny Rogers & Kim Carnes
- "Don't Leave Me Now" – Pink Floyd
- "Don't Let Go" – Isaac Hayes
- "Don't Say Goodnight (It's Time For Love)" – The Isley Brothers
- "Downtown" – Tom Waits
- "Dream About Fun" – Mark White
- "Dreamin" – Cliff Richard
- "Drive All Night" – Bruce Springsteen
- "Drivin' My Life Away" – Eddie Rabbitt
- "Duchess" – Genesis
- "Echo Beach" – Martha and the Muffins
- "Eighth Day" – Hazel O'Connor
- "The Electric Co." – U2
- "Embarrassment" – Madness
- "Emotional Rescue" – The Rolling Stones
- "Enjoy Yourself" – The Specials
- "Enola Gay" – OMD
- "Equinoxe (Part V)" – The Shadows
- "The Eternal" – Joy Division
- "Every Time You Go Away" – Hall & Oates
- "Every Woman in the World to Me" – Air Supply
- "Everybody Wants Some!!" – Van Halen
- "Everybody's Gotta Learn Sometime" – The Korgis
- "Expresso Love" – Dire Straits
- "Fade to Grey" – Visage
- "Fame" – Irene Cara
- "Fanmail" – The Dickies
- "Fantastic Voyage" – Lakeside
- "Fascist Architecture" – Bruce Cockburn
- "Fashion" – David Bowie
- "Fire Lake" – Bob Seger and the Silver Bullet Band
- "Fool for Your Loving" – Whitesnake
- "Forever Loving Jah" – Bob Marley and the Wailers
- "Freedom of Choice" – Devo
- "Games People Play" – The Alan Parsons Project
- "Games Without Frontiers" – Peter Gabriel
- "Gates of Steel" – Devo
- "Generals and Majors" – XTC
- "Geno" – Dexys Midnight Runners
- "Gigantor" – The Dickies
- "Gimme Some Lovin'" – The Blues Brothers
- "Girl U Want" – Devo
- "Give It All You Got" – Chuck Mangione
- "Give Me Back My Man" – The B-52's
- "Give Me the Night" – George Benson
- "Going Underground/The Dreams of Children" – The Jam
- "The Great Curve" – Talking Heads
- "Grim Traveller" – Bruce Cockburn
- "Guerilla Betrayed" – Bruce Cockburn
- "Guilty" – Barbra Streisand & Barry Gibb
- "The Guns of Brixton" – The Clash
- "Happy Birthday" – Stevie Wonder
- "Happy House" – Siouxie and the Banshees
- "The Hardest Part" – Blondie
- "Head Games" – Foreigner
- "Heart Hotels" – Dan Fogelberg
- "Heart of Glass" – The Shadows
- "Heartbreaker" – Pat Benatar
- "He's So Shy" – The Pointer Sisters
- "Hey Nineteen" – Steely Dan
- "High Fidelity" – Elvis Costello and the Attractions
- "Him" – Rupert Holmes
- "Hit Me With Your Best Shot" – Pat Benatar
- "Hold on Hold Out" – Jackson Browne
- "Hold on to My Love" – Jimmy Ruffin
- "Holiday in Cambodia" – Dead Kennedys
- "Horizontal Bop" – Bob Seger and the Silver Bullet Band
- "Hot Rod Hearts" – Robbie Dupree
- "How Do I Make You" – Linda Ronstadt
- "How Does It Feel To Be Back" – Hall & Oates
- "How I Wrote 'Elastic Man'" – The Fall
- "Hungry Heart" – Bruce Springsteen
- "Hurt So Bad" – Linda Ronstadt
- "I Can't Stand Up For Falling Down" – Elvis Costello
- "I Can't Tell You Why" – Eagles
- "I Die: You Die" – Gary Numan
- "I Don't Remember" – Peter Gabriel
- "I Don't Wanna Get Drafted" – Frank Zappa
- "I Got You" – Split Enz
- "I Know" – Bob Marley
- "I Owe You One" – Shalamar
- "I Shoulda Loved Ya" – Narada Michael Walden
- "I'm a Rocker" – Bruce Springsteen
- "I'm Alright" – Kenny Loggins
- "I'm Coming Out" – Diana Ross
- "I'm Ready" – Kano
- "I'm Happy Just to Dance with You" – Anne Murray
- "I Made It Through the Rain" – Barry Manilow
- "I Never Knew Love Like This Before" – Stephanie Mills
- "I Pledge My Love" – Peaches & Herb
- "I Wanna Be Sedated" – Ramones
- "I Wanna Be Your Lover" – Prince
- "I Want To Be Straight" – Ian Dury and the Blockheads
- "I Zimbra" – Talking Heads
- "Imitation of Christ" – The Psychedelic Furs
- "In America" – Charlie Daniels Band
- "In Every Dream Home (a Nightmare)" – Joe Jackson
- "In My Heart" – Freeway
- "In The Beginning There Was Rhythm" – The Slits
- "Independence Day" – Bruce Springsteen
- "India" – The Psychedelic Furs
- "Inside of You" – Ray, Goodman & Brown
- "International Jet Set" – The Specials
- "Into the Heart / Out of Control" – U2
- "Isolation" – Joy Division
- "Ita" – Cold Chisel
- "It's Different For Girls" – Joe Jackson
- "It's My Turn" – Diana Ross
- "It's Still Rock and Roll to Me" – Billy Joel
- "Ivan Meets G.I. Joe" – The Clash
- "Jane" – Jefferson Starship (released in 1979)
- "Jersey Girl" – Tom Waits
- "Jesse" – Carly Simon
- "Johnny Hit and Run Pauline" – X
- "JoJo" – Boz Scaggs
- "Jump Niyahbinghi" – Bob Marley & The Wailers
- "Just Can't Wait" – The J. Geils Band
- "(Just Like) Starting Over" – John Lennon
- "Keep Away" – Lou Reed
- "The Kid Is Hot Tonite" – Loverboy
- "Kill the Poor" – Dead Kennedys
- "Killer on the Loose" – Thin Lizzy
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- "Kings of the Wild Frontier" – Adam and the Ants
- "Kiss Me In the Rain" – Barbra Streisand
- "Kiss on My List" – Hall & Oates
- "Komakino" – Joy Division
- "Landlord" – Gladys Knight & the Pips
- "The Last of the New Wave Riders" – Utopia
- "Late in the Evening" – Paul Simon
- "Let Me Go" – The Rolling Stones
- "Let Me Love You Tonight" – Pure Prairie League
- "Let My Love Open the Door" – Pete Townshend
- "Let's Go Round Again" – Average White Band
- "Lip Up Fatty" – Bad Manners
- "Listening Wind" – Talking Heads
- "Little Jeannie" – Elton John
- "Living After Midnight" – Judas Priest
- "Living Through Another Cuba" – XTC
- "The Long Run" – Eagles
- "Longer" – Dan Fogelberg
- "London Calling" – The Clash
- "Look What You've Done to Me" – Boz Scaggs
- "Lookin' for Love" – Johnny Lee
- "Los Angeles" – X
- "Lost in Art" – Pere Ubu
- "Lost in Love" – Air Supply
- "Lost in the Supermarket" – The Clash
- "Love at First Night" – Kim Hart
- "Love Canal" – Flipper
- "Love on the Rocks" – Neil Diamond
- "Love Stinks" – The J. Geils Band
- "Love the World Away" – Kenny Rogers
- "Love TKO" – Teddy Pendergrass
- "Love Will Tear Us Apart" – Joy Division
- "Lovin', Touchin', Squeezin' " – Journey
- "The Magnificent Seven" – The Clash
- "Man Gave Names to All the Animals" – Bob Dylan
- "Man Next Door" – The Slits
- "Master Blaster (Jammin)" – Stevie Wonder
- "Me Myself I" – Joan Armatrading
- "Meltdown With the Ramones" (EP) – Ramones
- "Mirror in the Bathroom" – The Beat
- "Misunderstanding" – Genesis
- "Money" – Flying Lizards
- "Money Changes Everything" – The Brains
- "Monkey Suit/Squirm" (live) – Plasmatics
- "More Love" – Kim Carnes
- "More Than I Can Say" – Leo Sayer
- "Mozart 40" – The Shadows
- "Mr. Jones" – The Psychedelic Furs
- "My Baby" – Cold Chisel
- "My Old Piano" – Diana Ross
- "My Perfect Cousin" – The Undertones
- "Nausea" – X
- "Need Your Loving Tonight" – Queen
- "New Amsterdam" – Elvis Costello
- "Nie mehr allein sein" – Tony Holiday
- "No One Driving" – John Foxx
- "No Self Control" – Peter Gabriel
- "Non so che darei" – Alan Sorrenti
- "The Ocean" – U2
- "Off the Wall" – Michael Jackson
- "Oh Yeah (On The Radio)" – Roxy Music
- "The Old Homestead" – Neil Young
- "Old Pervert" – The Soft Boys
- "On the Radio" – Donna Summer
- "On the Road Again" – Willie Nelson
- "Once in a Lifetime" – Talking Heads
- "One Fine Day" – Carole King
- "One in a Million You" – Larry Graham
- "Out in the Street" – Bruce Springsteen
- "Over You" – Roxy Music
- "Paranoid Time" – The Minutemen
- "Party Out of Bounds" – The B-52's
- "People Who Died" – The Jim Carroll Band
- "Pilot of the Airwaves" – Charlie Dore
- "Play The Game" – Queen
- "Poison Ivy" – The Lambrettas
- "Police and Thieves" – Junior Murvin
- "Police on my Back" – The Clash
- "The Pop Group" – The Slits
- "Pop Muzik" – M
- "Private Idaho" – The B-52's
- "Private Life" – Grace Jones
- "Pulling Mussels (From The Shell)" – Squeeze
- "The Puppet – Echo & the Bunnymen
- "Putta Block" – The Fall
- "Quiche Lorraine" – The B-52's
- "Rastaman Live Up!" – Bob Marley
- "Rat Race" – The Specials
- "Real Love" – The Doobie Brothers
- "Real Situation" – Bob Marley
- "Rebel Waltz" – The Clash
- "Redemption Song" – Bob Marley & The Wailers
- "Refugee" – Tom Petty and the Heartbreakers
- "Requiem" – Killing Joke
- "Rescue" – Echo & the Bunnymen
- "Respectable Street" – XTC
- "Ride Like The Wind" – Christopher Cross
- "Riders in the Sky – The Shadows
- "Rise" – Herb Alpert
- "Rock And Roll Ain't Noise Pollution" – AC/DC
- "Rock Lobster" – The B-52's
- "Rocket From a Bottle" – XTC
- "Romeo and Juliet" – Dire Straits
- "Romeo's Tune" – Steve Forbert
- "The Rose" – Bette Midler
- "Run Like Hell" – Pink Floyd (released in 1979)
- "Sara" – Fleetwood Mac
- "Save Me" – Queen
- "Saved" – Bob Dylan
- "The Second Time Around" – Shalamar
- "September Morn" – Neil Diamond
- "Set Me Free" – Utopia
- "Seven Bridges Road" – Eagles
- "Sexy Eyes" – Dr. Hook
- "She's Out of My Life" – Michael Jackson
- "She's So Cold" – The Rolling Stones
- "Shining Star" – The Manhattans
- "Shoot Out the Lights – Diamond Head
- "Simon Templar/Two Pints of Lager and a Packet of Crisps" – Splodgenessabounds
- "Singing In The 80s" – The Monitors
- "Sister Europe" – The Psychedelic Furs
- "Skateaway" – Dire Straits
- "Sleeping With the Television On" – Billy Joel
- "So Lonely" – The Police
- "Sock It To 'em J.B." – The Specials
- "Solid Rock" – Bob Dylan
- "Sometimes a Fantasy" – Billy Joel
- "Spacer" – Sheila & B. Devotion
- "Spanish Bombs" – The Clash
- "The Special AKA Live EP" – The Specials
- "Special Brew" – Bad Manners
- "Special Lady" – Ray, Goodman & Brown
- "The Spirit of Radio" – Rush
- "Staring at the Rude Boys" – The Ruts
- "Start" – The Jam
- "State of the Heart" – Mondo Rock
- "Stayin' Power" – Neil Young
- "Steal Away" – Robbie Dupree
- "Stereotype" – The Specials
- "Stiff Necked Fools" – Bob Marley & The Wailers
- "Stomp" – The Brothers Johnson
- "Stop the Cavalry" – Jona Lewie
- "Stop Your Sobbing" – The Pretenders
- "Stories For Boys" – U2
- "Strangers on a Train" – The Sports
- "Strobe Light" – The B-52's
- "Suddenly" – Cliff Richard and Olivia Newton-John
- "Super Trouper" – ABBA
- "Take This Town" – XTC
- "Take Your Time (Do It Right)" – The S.O.S. Band
- "Talk of the Town" – The Pretenders
- "Tattooed Love Boys" – The Pretenders
- "Teach the Gifted Children" – Lou Reed
- "Tears of a Clown" – The Beat
- "Tell It Like It Is" – Heart
- "Ten Feet Tall" – XTC
- "Three Little Birds" – Bob Marley & The Wailers
- "That Girl Could Sing" – Jackson Browne
- "Theater" – Katja Ebstein
- "The Tide Is High" – Blondie
- "Theme from New York, New York" – Frank Sinatra
- "Think About Me" – Fleetwood Mac
- "This Feminine Position" – The Roches
- "This Is It" – Kenny Loggins
- "Time Out of Mind" – Steely Dan
- "Tired of Toein' the Line" – Rocky Burnette
- "To Cut a Long Story Short" – Spandau Ballet
- "Too Hot" – Kool and the Gang
- "Totally Wired" – The Fall
- "Touch" – U2
- "Touch and Go" – The Cars
- "Touch Too Much (Live)" – AC/DC
- "Train in Vain" – The Clash
- "Treat Me Right" – Pat Benatar
- "Tunnel of Love" – Dire Straits
- "Turn It on Again" – Genesis
- "Turn Me Loose" – Loverboy
- "Turning Japanese" – The Vapors
- "Twilight" – U2
- "Twilight Café" – Susan Fassbender
- "Twilight Zone/Twilight Tone" – The Manhattan Transfer
- "The Wanderer" – Donna Summer
- "Wait For Me" – Hall & Oates
- "Wait Til Your Boat Goes Down" – XTC
- "Wardance" – Killing Joke
- "Washington Bullets" – The Clash
- "Watching the Wheels" – John Lennon
- "Watching You" – Slave
- "We Are Glass" – Gary Numan
- "We Don't Talk Anymore" – Cliff Richard
- "Wedding Cake Island" – Midnight Oil
- "Wednesday Week" – The Undertones
- "What I Like About You" – The Romantics
- "Whip It" – Devo
- "Why Me?" – Styx
- "With You I'm Born Again" – Billy Preston & Syreeta Wright
- "Woman" – John Lennon
- "Working My Way Back to You" – The Spinners
- "Wrong 'Em Boyo" – The Clash
- "Yes, I'm Ready" – Teri DeSario with KC
- "You Better Run" – Pat Benatar
- "You May Be Right" – Billy Joel
- "You Shook Me All Night Long" – AC/DC
- "You'll Accomp'ny Me" – Bob Seger and the Silver Bullet Band
- "You'll Always Find Me in the Kitchen at Parties" – Jona Lewie
- "Young Miles in the Basement" – Pere Ubu
- "Your Phones Off the Hook, But You're Not" – X
- "You're Gonna Get What's Coming" – Bonnie Raitt
- "You're Lying" – Linx
- "You're Only Lonely" – J. D. Souther
- "You've Lost That Lovin' Feelin'" – Hall & Oates
- "The Zoo" – The Scorpions
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